The Correct Answer is B!

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A 68-year-old woman was brought in by ambulance to the ED after a car accident. She had a laceration of the right upper arm, but bleeding appears to be somewhat controlled with compression alone.

Medical history:



Medications: Apixaban 5 mg bid
Physical examination:

Blood pressure is 132/78 mm

HgHR is 88 bpm in AF

Laboratory results: CrCl 58 mL/minHGB 12.8 g/dL

What is your recommendation for managing this patient's bleed?

  1. Give prothrombin complex concentrate (PCC)
  2. Continue compression of the site and observe while holding the apixaban
  3. Infuse idarucizumab 5 mg total
  4. Transfuse fresh frozen plasma (FFP)
  5. Proceed with hemodialysis to remove the apixaban

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