Acute Decompensated Heart Failure

DeVore and colleagues’ (JAMA Cardiology, Dec 11) secondary analysis of the open-label extension of the PIONEER-HF examined the effect of switching from taking enalapril (10 mg twice daily) to sacubitril/valsartan on NT-proBNP levels. Their analyses suggest that early initiation of sacubitril/valsartan during hospitalization for stabilized patients with acute decompensated heart failure improves patient outcomes. Review…

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